Addiction And The Brain: How Drugs Impact The Brain
In the NAc, GABAergic projections, sent by the VTA, also synapse onto cholinergic interneurons (dark gray), thus inhibiting their excitatory input onto DA terminals. GABAergic and glutamatergic terminals in the NAc also have the capacity to modulate accumbal DA activity onto MSNs directly. Since these neurons also express MOR but some also CB1R (226, 361), …
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